An allergic reaction to the sulfonamides drugs is often referred to as “Sulfa allergy”.  Sulfonamides are some of the original antibacterial drugs.  It’s important to note that antibiotic sulfonamides are different structurally form non-antibiotic sulfonamides.  The antibiotic form is the more likely to trigger a sulfa allergy reaction.
The number of people affected by sulfa allergy is roughly the same as those who have similar reactions to other drugs such as penicillin.  People who have other issues such as immune problems which can cause them to metabolize drugs more slowly are more likely to have an allergic reaction.

Some sulfa allergy symptoms are mild while some reactions can be life threatening. Sulfa allergy can adversely affect various blood cells. This reaction results in fewer white blood cells, red blood cells and platelets.  This can leave a patient with increased risked for anemia, or infections. Sulfa allergy can react within the lung cause a pneumonia type illness. When a patient is suffering from asthma or heart issues this allergic reaction can worsen the condition and this can prove to be life threatening. Just as serious is the reaction which can occur in the liver and kidney.  Patients with a sulfa allergy can develop a type of hepatitis or kidney failure.

Skin reactions can be mild or dire. Skin rashes or hives can range from relatively benign rashes to the more life-threatening toxic epidermal necrolysis. Anyone taking this medication and experiencing a rash should try to avoid sunlight since this can exacerbate the problem. There is no way to pre-diagnosis a sulfa allergy. The only way to confirm someone is allergic is to careful monitor any course of this treatment for any signs of trouble. Once it is determined by a health care professional that a sulfa allergy is occurring the usual precaution is discontinue its use immediately.  Naturally, the next step is to treat the symptoms of the sulfa allergy especially in those with the more serious or severe conditions.

If a medical professional believes sulfa drugs are the most beneficial for a patient who shows a reaction there might be an attempt to desensitize the patient to the medication.  This is done by giving the patient small doses over time until they are able to have a full dose without a sulfa allergy reaction.